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A Mitochondria-Associated Oxidative Stress Perspective on Huntington’s Disease

Huntington’s disease (HD) is genetically caused by mutation of the Huntingtin (HTT) gene. At present, the mechanisms underlying the defect of HTT and the development of HD remain largely unclear. However, increasing evidence shows the presence of enhanced oxidative stress in HD patients. In this rev...

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Detalhes bibliográficos
Publicado no:Front Mol Neurosci
Main Authors: Zheng, Ju, Winderickx, Joris, Franssens, Vanessa, Liu, Beidong
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6156126/
https://ncbi.nlm.nih.gov/pubmed/30283298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2018.00329
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