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Impact of the Metal Center and Leaving Group on the Anticancer Activity of Organometallic Complexes of Pyridine-2-carbothioamide †

Ru(II)(cym)Cl (cym = η(6)-p-cymene) complexes of pyridinecarbothioamides have shown potential for development as orally active anticancer metallodrugs, underlined by their high selectivity towards plectin as the molecular target. In order to investigate the impact of the metal center on the anticanc...

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Publicat a:Molecules
Autors principals: Arshad, Jahanzaib, Tong, Kelvin K. H., Movassaghi, Sanam, Söhnel, Tilo, Jamieson, Stephen M. F., Hanif, Muhammad, Hartinger, Christian G.
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7914729/
https://ncbi.nlm.nih.gov/pubmed/33562622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26040833
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