New Quinoxaline Derivatives as Dual Pim-1/2 Kinase Inhibitors: Design, Synthesis and Biological Evaluation

Proviral integration site for Moloney murine leukemia virus (Pim)-1/2 kinase overexpression has been identified in a variety of hematologic (e.g., multiple myeloma or acute myeloid leukemia (AML)) and solid (e.g., colorectal carcinoma) tumors, playing a key role in cancer progression, metastasis, an...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Oyallon, Bruno, Brachet-Botineau, Marie, Logé, Cédric, Robert, Thomas, Bach, Stéphane, Ibrahim, Sajida, Raoul, William, Croix, Cécile, Berthelot, Pascal, Guillon, Jean, Pinaud, Noël, Gouilleux, Fabrice, Viaud-Massuard, Marie-Claude, Denevault-Sabourin, Caroline
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7914722/
https://ncbi.nlm.nih.gov/pubmed/33562106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26040867
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