Caffeic Acid Enhances the Anti-Leukemic Effect of Imatinib on Chronic Myeloid Leukemia Cells and Triggers Apoptosis in Cells Sensitive and Resistant to Imatinib

Among the phenolic acids tested on the K562 cell line, a model of chronic myeloid leukemia (CML), caffeic acid (CA) was biologically active on sensitive and imatinib (IM)-resistant cells at micro-molar concentration, either in terms of reduction of cell proliferation or triggering of apoptosis. The...

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Pubblicato in:Int J Mol Sci
Autori principali: Feriotto, Giordana, Tagliati, Federico, Giriolo, Riccardo, Casciano, Fabio, Tabolacci, Claudio, Beninati, Simone, Khan, Mahmud Tareq Hassan, Mischiati, Carlo
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2021
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7914550/
https://ncbi.nlm.nih.gov/pubmed/33562019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22041644
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