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SIRT3-mediated deacetylation of NLRC4 promotes inflammasome activation
Salmonella typhimurium (S. typhimurium) infection of macrophage induces NLRC4 inflammasome-mediated production of the pro-inflammatory cytokines IL-1β. Post-translational modifications on NLRC4 are critical for its activation. Sirtuin3 (SIRT3) is the most thoroughly studied mitochondrial nicotinamid...
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Publicado no: | Theranostics |
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Principais autores: | , , , , , , , , , , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Ivyspring International Publisher
2021
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7914345/ https://ncbi.nlm.nih.gov/pubmed/33664876 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.55573 |
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