SIRT3-mediated deacetylation of NLRC4 promotes inflammasome activation

Salmonella typhimurium (S. typhimurium) infection of macrophage induces NLRC4 inflammasome-mediated production of the pro-inflammatory cytokines IL-1β. Post-translational modifications on NLRC4 are critical for its activation. Sirtuin3 (SIRT3) is the most thoroughly studied mitochondrial nicotinamid...

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Detalhes bibliográficos
Publicado no:Theranostics
Main Authors: Guan, Chenyang, Huang, Xian, Yue, Jinnan, Xiang, Hongrui, Shaheen, Samina, Jiang, Zhenyan, Tao, Yuexiao, Tu, Jun, Liu, Zhenshan, Yao, Yufeng, Yang, Wen, Hou, Zhaoyuan, Liu, Junling, Yang, Xiao-Dong, Zou, Qiang, Su, Bing, Liu, Zhiduo, Ni, Jun, Cheng, Jinke, Wu, Xuefeng
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2021
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7914345/
https://ncbi.nlm.nih.gov/pubmed/33664876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.55573
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