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Supercharging BRD4 with NUT in carcinoma
NUT carcinoma (NC) is an extremely aggressive squamous cancer with no effective therapy. NC is driven, most commonly, by the BRD4-NUT fusion oncoprotein. BRD4-NUT combines the chromatin-binding bromo- and extraterminal domain-containing (BET) protein, BRD4, with an unstructured, poorly understood pr...
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| Published in: | Oncogene |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2021
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7914217/ https://ncbi.nlm.nih.gov/pubmed/33452461 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-020-01625-0 |
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