Utilizing Dynamic Contrast-Enhanced Magnetic Resonance Imaging (DCE-MRI) to Analyze Interstitial Fluid Flow and Transport in Glioblastoma and the Surrounding Parenchyma in Human Patients

Background: Glioblastoma (GBM) is the deadliest and most common brain tumor in adults, with poor survival and response to aggressive therapy. Limited access of drugs to tumor cells is one reason for such grim clinical outcomes. A driving force for therapeutic delivery is interstitial fluid flow (IFF...

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Vydáno v:Pharmaceutics
Hlavní autoři: Chatterjee, Krishnashis, Atay, Naciye, Abler, Daniel, Bhargava, Saloni, Sahoo, Prativa, Rockne, Russell C., Munson, Jennifer M.
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2021
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7913790/
https://ncbi.nlm.nih.gov/pubmed/33557069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics13020212
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