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TMOD-01. THE ROLE OF PERSISTENCE, PROLIFERATION, AND TUMOR CELL KILLING EFFICIENCY IN DETERMINING RESPONSE TO CAR T-CELL THERAPY IN GLIOBLASTOMA: A MATHEMATICAL MODEL AND ANALYSIS

Chimeric antigen receptor (CAR) T-cell therapy is a promising emerging area of immunotherapy for the treatment of recurrent glioblastoma. In this therapy, T-cells are genetically modified to target tumor-specific antigens. Efficacy of CAR T-cell therapy depends on several factors, including CAR T-ce...

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Publicado en:Neuro Oncol
Autores principales: Sahoo, Prativa, Abler, Daniel, Adhikarla, Vikram, Maestrini, Davide, Rockne, Russell
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6217176/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.1114
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