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Lamin B1 acetylation slows the G1 to S cell cycle transition through inhibition of DNA repair

The integrity and regulation of the nuclear lamina is essential for nuclear organization and chromatin stability, with its dysregulation being linked to laminopathy diseases and cancer. Although numerous posttranslational modifications have been identified on lamins, few have been ascribed a regulat...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Murray-Nerger, Laura A, Justice, Joshua L, Rekapalli, Pranav, Hutton, Josiah E, Cristea, Ileana M
Format: Artigo
Language:Inglês
Published: Oxford University Press 2021
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7913768/
https://ncbi.nlm.nih.gov/pubmed/33533922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkab019
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