Prolactin Rescues Immature B Cells from Apoptosis-Induced BCR-Aggregation through STAT3, Bcl2a1a, Bcl2l2, and Birc5 in Lupus-Prone MRL/lpr Mice

Self-reactive immature B cells are eliminated through apoptosis by tolerance mechanisms, failing to eliminate these cells results in autoimmune diseases. Prolactin is known to rescue immature B cells from B cell receptor engagement-induced apoptosis in lupus-prone mice. The objective of this study w...

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Pubblicato in:Cells
Autori principali: Flores-Fernández, Rocio, Aponte-López, Angélica, Suárez-Arriaga, Mayra C., Gorocica-Rosete, Patricia, Pizaña-Venegas, Alberto, Chávez-Sanchéz, Luis, Blanco-Favela, Francico, Fuentes-Pananá, Ezequiel M., Chávez-Rueda, Adriana K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2021
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7913714/
https://ncbi.nlm.nih.gov/pubmed/33557010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10020316
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