Mesenchymal stem cell exosome-derived miR-223 alleviates acute graft-versus-host disease via reducing the migration of donor T cells

BACKGROUND: Mesenchymal stem cells (MSCs) have been utilized in treating acute graft-versus-host disease (aGvHD) as they show strong immunosuppressive capacity through the release of various mediators, including immunosuppressive molecules, growth factors, chemokines, and exosomes. MicroRNAs (miRNAs...

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Detalhes bibliográficos
Publicado no:Stem Cell Res Ther
Main Authors: Liu, Weijiang, Zhou, Na, Liu, Yuanlin, Zhang, Wei, Li, Xue, Wang, Yang, Zheng, Rongxiu, Zhang, Yi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7913292/
https://ncbi.nlm.nih.gov/pubmed/33637123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-021-02159-2
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