Polymorphisms in Glyoxalase I Gene Are Not Associated with Glyoxalase I Expression in Whole Blood or Markers of Methylglyoxal Stress: The CODAM Study

Glyoxalase 1 (Glo1) is the rate-limiting enzyme in the detoxification of methylglyoxal (MGO) into D-lactate. MGO is a major precursor of advanced glycation endproducts (AGEs), and both are associated with development of age-related diseases. Since genetic variation in GLO1 may alter the expression a...

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Vydáno v:Antioxidants (Basel)
Hlavní autoři: Maasen, Kim, Hanssen, Nordin M. J., van der Kallen, Carla J. H., Stehouwer, Coen D. A., van Greevenbroek, Marleen M. J., Schalkwijk, Casper G.
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7913097/
https://ncbi.nlm.nih.gov/pubmed/33540757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antiox10020219
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