Associations of dicarbonyl stress with complement activation: the CODAM study

AIMS/HYPOTHESIS: Reactive α-dicarbonyl compounds are major precursors of AGEs and may lead to glycation of circulating and/or cell-associated complement regulators. Glycation of complement regulatory proteins can influence their capacity to inhibit complement activation. We investigated, in a human...

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Pubblicato in:Diabetologia
Autori principali: Xin, Ying, Hertle, Elisabeth, van der Kallen, Carla J. H., Schalkwijk, Casper G., Stehouwer, Coen D. A., van Greevenbroek, Marleen M. J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer Berlin Heidelberg 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7145776/
https://ncbi.nlm.nih.gov/pubmed/31993713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-020-05098-4
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