Pancreastatin Reduces Alternatively Activated Macrophages, Disrupts the Epithelial Homeostasis and Aggravates Colonic Inflammation. A Descriptive Analysis

Ulcerative colitis (UC) is characterized by modifying alternatively activated macrophages (AAM) and epithelial homeostasis. Chromogranin-A (CHGA), released by enterochromaffin cells, is elevated in UC and is implicated in inflammation progression. CHGA can be cleaved into several derived peptides, i...

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Bibliographic Details
Published in:Biomedicines
Main Authors: Eissa, Nour, Elgazzar, Omar, Hussein, Hayam, Hendy, Geoffrey N., Bernstein, Charles N., Ghia, Jean-Eric
Format: Artigo
Language:Inglês
Published: MDPI 2021
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7912769/
https://ncbi.nlm.nih.gov/pubmed/33535452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines9020134
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