Tetrahydrofurofuranoid Lignans, Eudesmin, Fargesin, Epimagnolin A, Magnolin, and Yangambin Inhibit UDP-Glucuronosyltransferase 1A1 and 1A3 Activities in Human Liver Microsomes

Eudesmin, fargesin, epimagnolin A, magnolin, and yangambin are tetrahydrofurofuranoid lignans with various pharmacological activities found in Magnoliae Flos. The inhibition potencies of eudesmin, fargesin, epimagnolin A, magnolin, and yangambin on six major human uridine 5′-diphospho-glucuronosyltr...

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Gepubliceerd in:Pharmaceutics
Hoofdauteurs: Park, Ria, Park, Eun Jeong, Cho, Yong-Yeon, Lee, Joo Young, Kang, Han Chang, Song, Im-Sook, Lee, Hye Suk
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2021
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7912740/
https://ncbi.nlm.nih.gov/pubmed/33535454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics13020187
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