Mycobacterium tuberculosis Rv0580c Impedes the Intracellular Survival of Recombinant Mycobacteria, Manipulates the Cytokines, and Induces ER Stress and Apoptosis in Host Macrophages via NF-κB and p38/JNK Signaling

The Mycobacterium tuberculosis (M. tb) genome encodes a large number of hypothetical proteins, which need to investigate their role in physiology, virulence, pathogenesis, and host interaction. To explore the role of hypothetical protein Rv0580c, we constructed the recombinant Mycobacterium smegmati...

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Bibliografiske detaljer
Udgivet i:	Pathogens
Main Authors:	Ali, Md Kaisar, Nzungize, Lambert, Abbas, Khushnood, Eckzechel, Nzaou Stech Anomene, Abo-kadoum, M. A., Moure, Ulrich Aymard Ekomi, Asaad, Mohammed, Alam, Aftab, Xu, Junqi, Xie, Jianping
Format:	Artigo
Sprog:	Inglês
Udgivet:	MDPI 2021
Fag:	Article
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC7912736/ https://ncbi.nlm.nih.gov/pubmed/33535567 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pathogens10020143
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Mycobacterium tuberculosis Rv0580c Impedes the Intracellular Survival of Recombinant Mycobacteria, Manipulates the Cytokines, and Induces ER Stress and Apoptosis in Host Macrophages via NF-κB and p38/JNK Signaling

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