Mycobacterium tuberculosis Rv0580c Impedes the Intracellular Survival of Recombinant Mycobacteria, Manipulates the Cytokines, and Induces ER Stress and Apoptosis in Host Macrophages via NF-κB and p38/JNK Signaling

The Mycobacterium tuberculosis (M. tb) genome encodes a large number of hypothetical proteins, which need to investigate their role in physiology, virulence, pathogenesis, and host interaction. To explore the role of hypothetical protein Rv0580c, we constructed the recombinant Mycobacterium smegmati...

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Detalhes bibliográficos
Publicado no:Pathogens
Main Authors: Ali, Md Kaisar, Nzungize, Lambert, Abbas, Khushnood, Eckzechel, Nzaou Stech Anomene, Abo-kadoum, M. A., Moure, Ulrich Aymard Ekomi, Asaad, Mohammed, Alam, Aftab, Xu, Junqi, Xie, Jianping
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7912736/
https://ncbi.nlm.nih.gov/pubmed/33535567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pathogens10020143
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