Effects of Nicorandil on Inflammation, Apoptosis and Atherosclerotic Plaque Progression

Nicorandil, a balanced vasodilator, is used in the second-line therapy of angina pectoris. In this study, we aimed to illuminate the effects of nicorandil on inflammation, apoptosis, and atherosclerotic plaque progression. Twenty-five LDL-R -/- mice were fed a high-fat diet for 14 weeks. After 6 wee...

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Bibliografiske detaljer
Udgivet i:Biomedicines
Main Authors: Lenz, Max, Kaun, Christoph, Krychtiuk, Konstantin A., Haider, Patrick, Brekalo, Mira, Maier, Nadine, Goederle, Laura, Binder, Christoph J., Huber, Kurt, Hengstenberg, Christian, Wojta, Johann, Hohensinner, Philipp J., Speidl, Walter S.
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7912627/
https://ncbi.nlm.nih.gov/pubmed/33513743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines9020120
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