Urokinase plasminogen activator protects cardiac myocytes from oxidative damage and apoptosis via hOGG1 induction

The role of uPA in tissue remodeling and cell migration is already well established. In addition, uPA was reported to stabilize p53, a key cell cycle control, DNA repair and apoptosis initiation protein. We aimed to determine the role of uPA-uPAR signaling towards cell survival or apoptosis in human...

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Detalhes bibliográficos
Publicado no:Apoptosis
Main Authors: Hohensinner, Philipp J., Takacs, Nikol, Kaun, Christoph, Thaler, Barbara, Krychtiuk, Konstantin A., Pfaffenberger, Stefan, Aliabadi, Arezu, Zuckermann, Andreas, Huber, Kurt, Wojta, Johann
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2017
Assuntos:
Short Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5486847/
https://ncbi.nlm.nih.gov/pubmed/28643198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10495-017-1388-9
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