PAI-1 (Plasminogen Activator Inhibitor-1) Expression Renders Alternatively Activated Human Macrophages Proteolytically Quiescent

OBJECTIVE—: Macrophages are versatile immune cells capable of polarizing into functional subsets depending on environmental stimulation. In atherosclerotic lesions, proinflammatory polarized macrophages are associated with symptomatic plaques, whereas Th2 (T-helper cell type 2) cytokine–polarized ma...

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Detalhes bibliográficos
Publicado no:Arterioscler Thromb Vasc Biol
Main Authors: Hohensinner, Philipp J., Baumgartner, Johanna, Kral-Pointner, Julia B., Uhrin, Pavel, Ebenbauer, Benjamin, Thaler, Barbara, Doberer, Konstantin, Stojkovic, Stefan, Demyanets, Svitlana, Fischer, Michael B., Huber, Kurt, Schabbauer, Gernot, Speidl, Walter S., Wojta, Johann
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2017
Assuntos:
Translational Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5627534/
https://ncbi.nlm.nih.gov/pubmed/28818858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.117.309383
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