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Molecular Modeling Studies on the Multistep Reactivation Process of Organophosphate-Inhibited Acetylcholinesterase and Butyrylcholinesterase

Poisoning with organophosphorus compounds used as pesticides or misused as chemical weapons remains a serious threat to human health and life. Their toxic effects result from irreversible blockade of the enzymes acetylcholinesterase and butyrylcholinesterase, which causes overstimulation of the chol...

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Библиографические подробности
Опубликовано в: :Biomolecules
Главные авторы: Jończyk, Jakub, Kukułowicz, Jędrzej, Łątka, Kamil, Malawska, Barbara, Jung, Young-Sik, Musilek, Kamil, Bajda, Marek
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2021
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7912477/
https://ncbi.nlm.nih.gov/pubmed/33513955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom11020169
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