Sensitivity of Osteosarcoma Cells to Concentration-Dependent Bioactivities of Lipid Peroxidation Product 4-Hydroxynonenal Depend on Their Level of Differentiation

4-Hydroxynonenal (HNE) is a major aldehydic product of lipid peroxidation known to exert several biological effects. Normal and malignant cells of the same origin express different sensitivity to HNE. We used human osteosarcoma cells (HOS) in different stages of differentiation in vitro, showing dif...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Sunjic, Suzana Borovic, Gasparovic, Ana Cipak, Jaganjac, Morana, Rechberger, Gerald, Meinitzer, Andreas, Grune, Tilman, Kohlwein, Sepp D., Mihaljevic, Branka, Zarkovic, Neven
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7912392/
https://ncbi.nlm.nih.gov/pubmed/33572933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10020269
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