Sensitivity of Osteosarcoma Cells to Concentration-Dependent Bioactivities of Lipid Peroxidation Product 4-Hydroxynonenal Depend on Their Level of Differentiation

4-Hydroxynonenal (HNE) is a major aldehydic product of lipid peroxidation known to exert several biological effects. Normal and malignant cells of the same origin express different sensitivity to HNE. We used human osteosarcoma cells (HOS) in different stages of differentiation in vitro, showing dif...

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Pubblicato in:Cells
Autori principali: Sunjic, Suzana Borovic, Gasparovic, Ana Cipak, Jaganjac, Morana, Rechberger, Gerald, Meinitzer, Andreas, Grune, Tilman, Kohlwein, Sepp D., Mihaljevic, Branka, Zarkovic, Neven
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2021
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7912392/
https://ncbi.nlm.nih.gov/pubmed/33572933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10020269
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