PPARα-Selective Antagonist GW6471 Inhibits Cell Growth in Breast Cancer Stem Cells Inducing Energy Imbalance and Metabolic Stress

Breast cancer is the most frequent cancer and the second leading cause of death among women. Triple-negative breast cancer is the most aggressive subtype of breast cancer and is characterized by the absence of hormone receptors and human epithelial growth factor receptor 2. Cancer stem cells (CSCs)...

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Vydáno v:Biomedicines
Hlavní autoři: Castelli, Vanessa, Catanesi, Mariano, Alfonsetti, Margherita, Laezza, Chiara, Lombardi, Francesca, Cinque, Benedetta, Cifone, Maria Grazia, Ippoliti, Rodolfo, Benedetti, Elisabetta, Cimini, Annamaria, d’Angelo, Michele
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7912302/
https://ncbi.nlm.nih.gov/pubmed/33525605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines9020127
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