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PPARα-Selective Antagonist GW6471 Inhibits Cell Growth in Breast Cancer Stem Cells Inducing Energy Imbalance and Metabolic Stress

Breast cancer is the most frequent cancer and the second leading cause of death among women. Triple-negative breast cancer is the most aggressive subtype of breast cancer and is characterized by the absence of hormone receptors and human epithelial growth factor receptor 2. Cancer stem cells (CSCs)...

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Detalhes bibliográficos
Publicado no:Biomedicines
Main Authors: Castelli, Vanessa, Catanesi, Mariano, Alfonsetti, Margherita, Laezza, Chiara, Lombardi, Francesca, Cinque, Benedetta, Cifone, Maria Grazia, Ippoliti, Rodolfo, Benedetti, Elisabetta, Cimini, Annamaria, d’Angelo, Michele
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7912302/
https://ncbi.nlm.nih.gov/pubmed/33525605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines9020127
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