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A New Perspective on the Origin of DNA Double-Strand Breaks and Its Implications for Ageing
It is estimated that 10–50 DNA double-strand breaks (DSBs) occur in a nucleated human cell per cell cycle. We reviewed the present state of knowledge and hypothesized that the currently accepted mechanisms cannot explain such high frequency of DSBs occurring daily under normal physiological conditio...
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| Veröffentlicht in: | Genes (Basel) |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
MDPI
2021
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7912064/ https://ncbi.nlm.nih.gov/pubmed/33530310 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes12020163 |
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