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Antiviral Activity of the G-Quadruplex Ligand TMPyP4 against Herpes Simplex Virus-1
The herpes simplex virus 1 (HSV-1) genome is extremely rich in guanine tracts that fold into G-quadruplexes (G4s), nucleic acid secondary structures implicated in key biological functions. Viral G4s were visualized in HSV-1 infected cells, with massive virus cycle-dependent G4-formation peaking duri...
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| Udgivet i: | Viruses |
|---|---|
| Main Authors: | , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
MDPI
2021
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7911665/ https://ncbi.nlm.nih.gov/pubmed/33525505 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v13020196 |
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