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An Update on Self-Amplifying mRNA Vaccine Development
This review will explore the four major pillars required for design and development of an saRNA vaccine: Antigen design, vector design, non-viral delivery systems, and manufacturing (both saRNA and lipid nanoparticles (LNP)). We report on the major innovations, preclinical and clinical data reported...
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| Publicado no: | Vaccines (Basel) |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7911542/ https://ncbi.nlm.nih.gov/pubmed/33525396 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/vaccines9020097 |
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