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Activation of Nrf2 by Electrophiles Is Largely Independent of the Selenium Status of HepG2 Cells

Selenoenzymes, whose activity depends on adequate selenium (Se) supply, and phase II enzymes, encoded by target genes of nuclear factor erythroid 2-related factor 2 (Nrf2), take part in governing cellular redox homeostasis. Their interplay is still not entirely understood. Here, we exposed HepG2 hep...

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Détails bibliographiques
Publié dans:Antioxidants (Basel)
Auteurs principaux: Tauber, Sarah, Sieckmann, Maria Katharina, Erler, Katrin, Stahl, Wilhelm, Klotz, Lars-Oliver, Steinbrenner, Holger
Format: Artigo
Langue:Inglês
Publié: MDPI 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7911449/
https://ncbi.nlm.nih.gov/pubmed/33498683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antiox10020167
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