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Activation of Nrf2 by Electrophiles Is Largely Independent of the Selenium Status of HepG2 Cells

Selenoenzymes, whose activity depends on adequate selenium (Se) supply, and phase II enzymes, encoded by target genes of nuclear factor erythroid 2-related factor 2 (Nrf2), take part in governing cellular redox homeostasis. Their interplay is still not entirely understood. Here, we exposed HepG2 hep...

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Detalhes bibliográficos
Publicado no:Antioxidants (Basel)
Main Authors: Tauber, Sarah, Sieckmann, Maria Katharina, Erler, Katrin, Stahl, Wilhelm, Klotz, Lars-Oliver, Steinbrenner, Holger
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7911449/
https://ncbi.nlm.nih.gov/pubmed/33498683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antiox10020167
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