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Identification and Characterization of Four c-di-GMP-Metabolizing Enzymes from Streptomyces ghanaensis ATCC14672 Involved in the Regulation of Morphogenesis and Moenomycin A Biosynthesis

Diguanylate cyclases (DGCs) and phosphodiesterases (PDEs) are essential enzymes deputed to maintain the intracellular homeostasis of the second messenger cyclic dimeric (3′→5′) GMP (c-di-GMP). Recently, c-di-GMP has emerged as a crucial molecule for the streptomycetes life cycle, governing both morp...

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Bibliografische gegevens
Gepubliceerd in:Microorganisms
Hoofdauteurs: Nuzzo, Desirèe, Makitrynskyy, Roman, Tsypik, Olga, Bechthold, Andreas
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2021
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7911125/
https://ncbi.nlm.nih.gov/pubmed/33573171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/microorganisms9020284
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