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Cyclic di-GMP cyclase SSFG_02181 from Streptomyces ghanaensis ATCC14672 regulates antibiotic biosynthesis and morphological differentiation in streptomycetes

Streptomycetes are filamentous bacteria famous for their ability to produce a vast majority of clinically important secondary metabolites. Both complex morphogenesis and onset of antibiotic biosynthesis are tightly linked in streptomycetes and require series of specific signals for initiation. Cycli...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Nuzzo, Desirèe, Makitrynskyy, Roman, Tsypik, Olga, Bechthold, Andreas
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7374567/
https://ncbi.nlm.nih.gov/pubmed/32694623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-68856-9
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