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Circulating exosomes and gut microbiome induced insulin resistance in mice exposed to intermittent hypoxia: Effects of physical activity

BACKGROUND: Gut microbiota (GM) contribute to obesity and insulin resistance (IR). Obstructive sleep apnea (OSA), characterized by intermittent hypoxia (IH), promotes IR and alters GM. Since circulating exosomes are implicated in IR, we examined the effects of IH and physical activity (PA) in mice o...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:EBioMedicine
Prif Awduron: Khalyfa, Abdelnaby, Ericsson, Aaron, Qiao, Zhuanghong, Almendros, Isaac, Farré, Ramon, Gozal, David
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Elsevier 2021
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7910674/
https://ncbi.nlm.nih.gov/pubmed/33485839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2021.103208
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