Circulating exosomes and gut microbiome induced insulin resistance in mice exposed to intermittent hypoxia: Effects of physical activity

BACKGROUND: Gut microbiota (GM) contribute to obesity and insulin resistance (IR). Obstructive sleep apnea (OSA), characterized by intermittent hypoxia (IH), promotes IR and alters GM. Since circulating exosomes are implicated in IR, we examined the effects of IH and physical activity (PA) in mice o...

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Bibliographic Details
Published in:EBioMedicine
Main Authors: Khalyfa, Abdelnaby, Ericsson, Aaron, Qiao, Zhuanghong, Almendros, Isaac, Farré, Ramon, Gozal, David
Format: Artigo
Language:Inglês
Published: Elsevier 2021
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7910674/
https://ncbi.nlm.nih.gov/pubmed/33485839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2021.103208
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