Circulating exosomes and gut microbiome induced insulin resistance in mice exposed to intermittent hypoxia: Effects of physical activity

BACKGROUND: Gut microbiota (GM) contribute to obesity and insulin resistance (IR). Obstructive sleep apnea (OSA), characterized by intermittent hypoxia (IH), promotes IR and alters GM. Since circulating exosomes are implicated in IR, we examined the effects of IH and physical activity (PA) in mice o...

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Dades bibliogràfiques
Publicat a:EBioMedicine
Autors principals: Khalyfa, Abdelnaby, Ericsson, Aaron, Qiao, Zhuanghong, Almendros, Isaac, Farré, Ramon, Gozal, David
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2021
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7910674/
https://ncbi.nlm.nih.gov/pubmed/33485839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2021.103208
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