Cancer-associated fibroblast-derived SDF-1 induces epithelial-mesenchymal transition of lung adenocarcinoma via CXCR4/β-catenin/PPARδ signalling

Cancer-associated fibroblasts (CAFs) contribute to tumour epithelial-mesenchymal transition (EMT) via interaction with cancer cells. However, the molecular mechanisms underlying tumour-promoting EMT of CAFs in lung adenocarcinoma (ADC) remain unclear. Here, we observed that CAFs isolated from lung A...

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Détails bibliographiques
Publié dans:Cell Death Dis
Auteurs principaux: Wang, Yingyan, Lan, Wen, Xu, Mingxin, Song, Jing, Mao, Jun, Li, Chunyan, Du, Xiaohui, Jiang, Yunling, Li, Encheng, Zhang, Rui, Wang, Qi
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2021
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7910618/
https://ncbi.nlm.nih.gov/pubmed/33637678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-03509-x
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