Structure-guided insights into heterocyclic ring-cleavage catalysis of the non-heme Fe (II) dioxygenase NicX

Biodegradation of aromatic and heterocyclic compounds requires an oxidative ring cleavage enzymatic step. Extensive biochemical research has yielded mechanistic insights about catabolism of aromatic substrates; yet much less is known about the reaction mechanisms underlying the cleavage of heterocyc...

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Bibliographic Details
Published in:Nat Commun
Main Authors: Liu, Gongquan, Zhao, Yi-Lei, He, Fangyuan, Zhang, Peng, Ouyang, Xingyu, Tang, Hongzhi, Xu, Ping
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2021
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7910607/
https://ncbi.nlm.nih.gov/pubmed/33637718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-21567-9
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