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LONP1 and ClpP cooperatively regulate mitochondrial proteostasis for cancer cell survival

Mitochondrial proteases are key components in mitochondrial stress responses that maintain proteostasis and mitochondrial integrity in harsh environmental conditions, which leads to the acquisition of aggressive phenotypes, including chemoresistance and metastasis. However, the molecular mechanisms...

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Detalles Bibliográficos
Publicado en:Oncogenesis
Main Authors: Lee, Yu Geon, Kim, Hui Won, Nam, Yeji, Shin, Kyeong Jin, Lee, Yu Jin, Park, Do Hong, Rhee, Hyun-Woo, Seo, Jeong Kon, Chae, Young Chan
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7910295/
https://ncbi.nlm.nih.gov/pubmed/33637676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41389-021-00306-1
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