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In Vivo Imaging of Local Inflammation: Monitoring LPS-Induced CD80/CD86 Upregulation by PET

PURPOSE: The co-stimulatory molecules CD80 and CD86 are upregulated on activated antigen-presenting cells (APC). We investigated whether local APC activation, induced by subcutaneous (s.c.) inoculation of lipopolysaccharides (LPS), can be imaged by positron emission tomography (PET) with CD80/CD86-t...

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Detalhes bibliográficos
Publicado no:Mol Imaging Biol
Main Authors: Taddio, Marco F., Castro Jaramillo, Claudia A., Runge, Peter, Blanc, Alain, Keller, Claudia, Talip, Zeynep, Béhé, Martin, van der Meulen, Nicholas P., Halin, Cornelia, Schibli, Roger, Krämer, Stefanie D.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7910267/
https://ncbi.nlm.nih.gov/pubmed/32989622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11307-020-01543-3
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