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Combined cellomics and proteomics analysis reveals shared neuronal morphology and molecular pathway phenotypes for multiple schizophrenia risk genes

An enigma in studies of neuropsychiatric disorders is how to translate polygenic risk into disease biology. For schizophrenia, where > 145 significant GWAS loci have been identified and only a few genes directly implicated, addressing this issue is a particular challenge. We used a combined cello...

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Bibliografische gegevens
Gepubliceerd in:Mol Psychiatry
Hoofdauteurs: Rosato, Martina, Stringer, Sven, Gebuis, Titia, Paliukhovich, Iryna, Li, Ka Wan, Posthuma, Danielle, Sullivan, Patrick F., Smit, August B., van Kesteren, Ronald E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7910218/
https://ncbi.nlm.nih.gov/pubmed/31142819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41380-019-0436-y
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