DUCT reveals architectural mechanisms contributing to bile duct recovery in a mouse model for Alagille syndrome

Organ function depends on tissues adopting the correct architecture. However, insights into organ architecture are currently hampered by an absence of standardized quantitative 3D analysis. We aimed to develop a robust technology to visualize, digitalize, and segment the architecture of two tubular...

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Veröffentlicht in:eLife
Hauptverfasser: Hankeova, Simona, Salplachta, Jakub, Zikmund, Tomas, Kavkova, Michaela, Van Hul, Noémi, Brinek, Adam, Smekalova, Veronika, Laznovsky, Jakub, Dawit, Feven, Jaros, Josef, Bryja, Vítězslav, Lendahl, Urban, Ellis, Ewa, Nemeth, Antal, Fischler, Björn, Hannezo, Edouard, Kaiser, Jozef, Andersson, Emma Rachel
Format: Artigo
Sprache:Inglês
Veröffentlicht: eLife Sciences Publications, Ltd 2021
Schlagworte:
Physics of Living Systems
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7909953/
https://ncbi.nlm.nih.gov/pubmed/33635272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.60916
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