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Contrast enhanced X-ray computed tomography imaging of amyloid plaques in Alzheimer disease rat model on lab based micro CT system

Amyloid plaques are small (~ 50 μm), highly-dense aggregates of amyloid beta (Aβ) protein in brain tissue, supposed to play a key role in pathogenesis of Alzheimer’s disease (AD). Plaques´ in vivo detection, spatial distribution and quantitative characterization could be an essential marker in diagn...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kavkova, Michaela, Zikmund, Tomas, Kala, Annu, Salplachta, Jakub, Proskauer Pena, Stephanie L., Kaiser, Josef, Jezek, Karel
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7966753/
https://ncbi.nlm.nih.gov/pubmed/33727592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-84579-x
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