Short-term exposure to intermittent hypoxia leads to changes in gene expression seen in chronic pulmonary disease

Obstructive sleep apnea (OSA) results from episodes of airway collapse and intermittent hypoxia (IH) and is associated with a host of health complications. Although the lung is the first organ to sense changes in oxygen levels, little is known about the consequences of IH to the lung hypoxia-inducib...

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Pubblicato in:eLife
Autori principali: Wu, Gang, Lee, Yin Yeng, Gulla, Evelyn M, Potter, Andrew, Kitzmiller, Joseph, Ruben, Marc D, Salomonis, Nathan, Whitsett, Jeffery A, Francey, Lauren J, Hogenesch, John B, Smith, David F
Natura: Artigo
Lingua:Inglês
Pubblicazione: eLife Sciences Publications, Ltd 2021
Soggetti:
Chromosomes and Gene Expression
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7909952/
https://ncbi.nlm.nih.gov/pubmed/33599610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.63003
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