Calcium Signaling and Mitochondrial Function in Presenilin 2 Knock-Out Mice: Looking for Any Loss-of-Function Phenotype Related to Alzheimer’s Disease

Alzheimer′s disease (AD) is the most common age-related neurodegenerative disorder in which learning, memory and cognitive functions decline progressively. Familial forms of AD (FAD) are caused by mutations in amyloid precursor protein (APP), presenilin 1 (PSEN1) and presenilin 2 (PSEN2) genes. Pres...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Rossi, Alice, Galla, Luisa, Gomiero, Chiara, Zentilin, Lorena, Giacca, Mauro, Giorgio, Valentina, Calì, Tito, Pozzan, Tullio, Greotti, Elisa, Pizzo, Paola
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7909802/
https://ncbi.nlm.nih.gov/pubmed/33494218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10020204
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