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Presenilin-2 and Calcium Handling: Molecules, Organelles, Cells and Brain Networks
Presenilin-2 (PS2) is one of the three proteins that are dominantly mutated in familial Alzheimer’s disease (FAD). It forms the catalytic core of the γ-secretase complex—a function shared with its homolog presenilin-1 (PS1)—the enzyme ultimately responsible of amyloid-β (Aβ) formation. Besides its e...
Kaydedildi:
| Yayımlandı: | Cells |
|---|---|
| Asıl Yazarlar: | , , , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
MDPI
2020
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7601421/ https://ncbi.nlm.nih.gov/pubmed/32992716 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9102166 |
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