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Lack of Autophagy Induction by Lithium Decreases Neuroprotective Effects in the Striatum of Aged Rats

The pharmacological modulation of autophagy is considered a promising neuroprotective strategy. While it has been postulated that lithium regulates this cellular process, the age-related effects have not been fully elucidated. Here, we evaluated lithium-mediated neuroprotective effects in young and...

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Библиографические подробности
Опубликовано в: :Pharmaceutics
Главные авторы: Costa, Angelica Jardim, Erustes, Adolfo Garcia, Sinigaglia, Rita, Girardi, Carlos Eduardo Neves, Pereira, Gustavo José da Silva, Ureshino, Rodrigo Portes, Smaili, Soraya Soubhi
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2021
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7909773/
https://ncbi.nlm.nih.gov/pubmed/33494241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics13020135
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