Effects of ICI 182,780, an ERα and ERβ antagonist, and G-1, a GPER agonist, on autophagy in breast cancer cells

OBJECTIVE: To investigate if ICI 182,780 (fulvestrant), a selective estrogen receptor alpha/beta (ERα/ERβ) antagonist, and G-1, a selective G-protein-coupled receptor (GPER) agonist, can potentially induce autophagy in breast cancer cell lines MCF-7 and SKBr3, and how G-1 affects cell viability. MET...

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Detalles Bibliográficos
Publicado en:Einstein (Sao Paulo)
Main Authors: Muler, Mari Luminosa, Antunes, Fernanda, Guarache, Gabriel Cicolin, Oliveira, Rafaela Brito, Ureshino, Rodrigo Portes, Bincoletto, Claudia, Pereira, Gustavo José da Silva, Smaili, Soraya Soubhi
Formato: Artigo
Idioma:Inglês
Publicado: Instituto Israelita de Ensino e Pesquisa Albert Einstein 2020
Assuntos:
Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7155941/
https://ncbi.nlm.nih.gov/pubmed/32321078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.31744/einstein_journal/2020AO4560
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