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Enhancing Top-Down Proteomics Data Analysis by Combining Deconvolution Results through a Machine Learning Strategy

Top-down mass spectrometry (MS) is a powerful tool for identification and comprehensive characterization of proteoforms arising from alternative splicing, sequence variation, and post-translational modifications. However, the complex dataset generated from top-down MS experiments requires multiple s...

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Bibliografiske detaljer
Udgivet i:J Am Soc Mass Spectrom
Main Authors: McIlwain, Sean J., Wu, Zhijie, Wetzel, Molly, Belongia, Daniel, Jin, Yutong, Wenger, Kent, Ong, Irene M., Ge, Ying
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7909725/
https://ncbi.nlm.nih.gov/pubmed/32223200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jasms.0c00035
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