Population Pharmacokinetics Analysis of Amikacin Initial Dosing Regimen in Elderly Patients

There are limited data of amikacin pharmacokinetics (PK) in the elderly population. Hence, we aimed to describe the population PK of amikacin in elderly patients (>70 years old) and to establish optimized initial dosing regimens. We simulated individual maximum concentrations in plasma (Cmax) and...

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發表在:Antibiotics (Basel)
Main Authors: Kato, Hideo, Parker, Suzanne L., Roberts, Jason A., Hagihara, Mao, Asai, Nobuhiro, Yamagishi, Yuka, Paterson, David L., Mikamo, Hiroshige
格式: Artigo
語言:Inglês
出版: MDPI 2021
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7909551/
https://ncbi.nlm.nih.gov/pubmed/33498481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antibiotics10020100
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