Evaluation of Amikacin Pharmacokinetics and Pharmacodynamics for Optimal Initial Dosing Regimen

Amikacin has been one of the important antimicrobial agents against Gram-negative pathogens. However, there is discrepancy regarding the amikacin initial dosage, with some reports recently recommending ≥25 mg/kg and others the conventional dosage (15–20 mg/kg). Hence, we evaluated the optimal initia...

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Bibliographic Details
Published in:Drugs R D
Main Authors: Kato, Hideo, Hagihara, Mao, Hirai, Jun, Sakanashi, Daisuke, Suematsu, Hiroyuki, Nishiyama, Naoya, Koizumi, Yusuke, Yamagishi, Yuka, Matsuura, Katsuhiko, Mikamo, Hiroshige
Format: Artigo
Language:Inglês
Published: Springer International Publishing 2017
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Original Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5318333/
https://ncbi.nlm.nih.gov/pubmed/28063020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40268-016-0165-5
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