Rhinovirus-induced CCL17 and CCL22 in Asthma Exacerbations and Differential Regulation by STAT6

The interplay of type-2 inflammation and antiviral immunity underpins asthma exacerbation pathogenesis. Virus infection induces type-2 inflammation–promoting chemokines CCL17 and CCL22 in asthma; however, mechanisms regulating induction are poorly understood. By using a human rhinovirus (RV) challen...

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Detalhes bibliográficos
Publicado no:Am J Respir Cell Mol Biol
Main Authors: Williams, Teresa C., Jackson, David J., Maltby, Steven, Walton, Ross P., Ching, Yee-Mann, Glanville, Nicholas, Singanayagam, Aran, Brewins, Jennifer J., Clarke, Deborah, Hirsman, Aurica G., Loo, Su-Ling, Wei, Lan, Beale, Janine E., Casolari, Paolo, Caramori, Gaetano, Papi, Alberto, Belvisi, Maria, Wark, Peter A. B., Johnston, Sebastian L., Edwards, Michael R., Bartlett, Nathan W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2021
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7909342/
https://ncbi.nlm.nih.gov/pubmed/33264064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2020-0011OC
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