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Impaired Alignment of Bone Matrix Microstructure Associated with Disorganized Osteoblast Arrangement in Malignant Melanoma Metastasis

Malignant melanoma favors spreading to bone, resulting in a weakened bone with a high fracture risk. Here, we revealed the disorganized alignment of apatite crystals in the bone matrix associated with the homing of cancer cells by developing an artificially controlled ex vivo melanoma bone metastasi...

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Detalhes bibliográficos
Publicado no:Biomolecules
Main Authors: Matsugaki, Aira, Kimura, Yumi, Watanabe, Ryota, Nakamura, Fumihito, Takehana, Ryo, Nakano, Takayoshi
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7909255/
https://ncbi.nlm.nih.gov/pubmed/33498283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom11020131
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