Impaired Alignment of Bone Matrix Microstructure Associated with Disorganized Osteoblast Arrangement in Malignant Melanoma Metastasis

Malignant melanoma favors spreading to bone, resulting in a weakened bone with a high fracture risk. Here, we revealed the disorganized alignment of apatite crystals in the bone matrix associated with the homing of cancer cells by developing an artificially controlled ex vivo melanoma bone metastasi...

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Vydáno v:Biomolecules
Hlavní autoři: Matsugaki, Aira, Kimura, Yumi, Watanabe, Ryota, Nakamura, Fumihito, Takehana, Ryo, Nakano, Takayoshi
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7909255/
https://ncbi.nlm.nih.gov/pubmed/33498283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom11020131
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